Simian 2.2 PRO
FV is transmitted via Semen and Bloodsucking Midges in a species-specific manner . The genus Simian Foamyvirus (SFV) was recently added to separate the SFVs into four distinct genera: FV, most known viruses of natural hosts are Pipistrellus and Macaca and Hylobates; Saguinus virus; Peromyscus virus, all seem to be of human origin ; and a new genus, Miomys virus. FVs have been known to be broadly distributed among primates. However, the detection rate of sequences for FVs from non-human primates is relatively low. Only one experimental evidence of a natural infection with FV was published . Here, we report four FV infections in a sample of orangutan, two in greater spot-nosed monkey, and one in capuchin monkey from Peninsular Malaysia and one in the Philippines. Up to now, almost half of all FV infections reported in macaques have been obtained from monkeys in the Philippines . In contrast to this, there are far less reports of FV infections in non-human primates in Malaysia and the other Southeast Asian nations. As such, this is the first discovery of SFV in individuals of the Cercopithecidae family. Consequently, this discovery of SFV in primates in Peninsular Malaysia highlights the need to conduct further studies on the prevalence of FV in non-human primates in Malaysia.
The phylogenetic tree constructed from the PFV proviral sequences showed the Cercopithecid SFV were clustered in two separate clades. The Cercopithecid genus species on which the Cercopithecus isolates lodged were grouped within either Cercopithecus baboonus or Hylobates latifrons clade. In this context, the Hylobates isolates were clustered together with Cercopithecus SPPV in which both Colombian isolates were subgrouped as one clade exhibiting a high bootstrap support value (86).